This problem occurs when the file extension type does not match a known MIME type. Because Office 2007 was released after IIS6, it doesn't understand the new MIME types for .docx, xlsx, etc from Office 2007
Check out this page for help on configuring them in IIS
http://www.jameskovacs.com/blog/ConfiguringIIS6ToServeOffice2007FileFormats.aspxNote, you must configure the MIME types identical for forward facing and back end servers for it to resolve this problem and you must restart IIS on any system that did not have the proper MIME types.