Do you mean new configuration, or save and migrate old configurations from Office 2003?
For example if you like to define a default language...this should be done in the normal.dotm which can be deployed afterwards
Settings on the Quick Access Toolbar are stored in .qat files which you can deploy, too
Also there are some other user settings which can be defnied in the Office Customization Tool (predefinded) or via group policy (forced)
Here are some links, how to migrate some settings
http://pleasepressanykey.blogspot.com/2008/03/restore-custom.htmlhttp://pleasepressanykey.blogspot.com/2008/03/automatically-restore-autotext-entries.html