When you set up your Client Access (OWA) server, ActiveSync is enabled by default. If your CA server is accessible from the world via a domain name (like mail.domain.com), you should be able to point your mobile device to that domain and, with proper credentials, it should connect properly.
Depending on the device, you may need to use domain\username as the username, if there is no specific place to enter the domain. You may also need to acquire an SSL certificate that is signed by a root authority, as some devices have a built-in set of root authorities and will refuse to trust anything else. The cert needs to be installed on your CA server.