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select * from yourtable where (yourcolumn1 = [Forms]![frmCatSrch]![Combo11] or [Forms]![frmCatSrch]![Combo11] is null) and (yourcolumn2 = [Forms]![frmCatSrch]![Combo12] or [Forms]![frmCatSrch]![Combo12] is null) and ... and so on ....